HapticV1, Main, Exploration, bibRecord, 006B55

Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge

Identifieur interne : 006B55 ( Main/Exploration ); précédent : 006B54; suivant : 006B56

Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge

Auteurs : Liliana Werner [États-Unis] ; Nick Mamalis [États-Unis] ; Suresh K. Pandey [États-Unis] ; Andrea M. Izak [États-Unis] ; Christian D. Nilson [États-Unis] ; Brandon L. Davis [États-Unis] ; Christopher Weight [États-Unis] ; David J. Apple [États-Unis]

Source :

Journal of cataract and refractive surgery [ 0886-3350 ] ; 2004.

RBID : Pascal:05-0001728

Descripteurs français

Pascal (Inist)
- Postérieur, Capsule, Gélule, Opacification, Animal, Lapin, Oeil, Ophtalmologie, Implant, Hydrophilie, Lentille intraoculaire, Bord, Chirurgie, Traitement.
Wicri :
- topic : Lapin, Chirurgie.

English descriptors

KwdEn :
- Acrylic Resins, Animal, Animals, Biocompatible Materials, Capsule, Cataract (etiology), Cataract (prevention & control), Edge, Eye, Hard capsule, Hydrophily, Implant, Intraocular lens, Lens Capsule, Crystalline (pathology), Lens Implantation, Intraocular (adverse effects), Lenses, Intraocular (adverse effects), Opacification, Ophthalmology, Posterior, Postoperative Complications, Prosthesis Design, Rabbit, Rabbits, Surgery, Treatment.
MESH :
- chemical : Acrylic Resins, Biocompatible Materials.
- adverse effects : Lens Implantation, Intraocular, Lenses, Intraocular.
- etiology : Cataract.
- pathology : Lens Capsule, Crystalline.
- prevention & control : Cataract.
- Animals, Postoperative Complications, Prosthesis Design, Rabbits.

Abstract

Purpose: To evaluate the development of posterior capsule opacification (PCO) after implantation of single-piece hydrophilic acrylic intraocular lenses (lOLs) with an enhanced square edge. Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. Methods: The standard 570H Centerflex (Rayner Ltd.) design was compared to 2 new designs with enhanced square edges: the 570E and the 570C. Ten lOLs of each type were implanted in a randomized manner by the same surgeon in 15 pigmented rabbits. After a follow-up of 3 weeks, the rabbits were killed and the eyes were analyzed from the posterior view. The intensity of central PCO, peripheral PCO, and Soemmering's ring formation was graded from 0 to 4. The area of Soemmering's ring was graded from 0 to 4 based on the number of quadrants involved. Other parameters analyzed were capsulorhexis coverage of the IOL edge and IOL centration and fixation. Results from the posterior view were complemented by histopathological evaluation. Results: Posterior capsule opacification was lowest in the 570C group, highest in the 570H group, and intermediate in the 570E group. There was a statistically significant difference between the 3 groups in peripheral PCO (P = .039). No significant difference was found between the groups in the other parameters analyzed. When cell ingrowth occurred with the 570H, it started at the optic-haptic junctions, as observed during the clinical follow-up and confirmed by gross and histopathological analyses. Conclusions: The square optic edge is the most important IOL design feature for PCO prevention. However, it should be present for 360 degrees around the IOL optic to provide an effective barrier effect.

Affiliations:

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins</term>
<term>Animal</term>
<term>Animals</term>
<term>Biocompatible Materials</term>
<term>Capsule</term>
<term>Cataract (etiology)</term>
<term>Cataract (prevention & control)</term>
<term>Edge</term>
<term>Eye</term>
<term>Hard capsule</term>
<term>Hydrophily</term>
<term>Implant</term>
<term>Intraocular lens</term>
<term>Lens Capsule, Crystalline (pathology)</term>
<term>Lens Implantation, Intraocular (adverse effects)</term>
<term>Lenses, Intraocular (adverse effects)</term>
<term>Opacification</term>
<term>Ophthalmology</term>
<term>Posterior</term>
<term>Postoperative Complications</term>
<term>Prosthesis Design</term>
<term>Rabbit</term>
<term>Rabbits</term>
<term>Surgery</term>
<term>Treatment</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Acrylic Resins</term>
<term>Biocompatible Materials</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cataract</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cataract</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Postoperative Complications</term>
<term>Prosthesis Design</term>
<term>Rabbits</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Postérieur</term>
<term>Capsule</term>
<term>Gélule</term>
<term>Opacification</term>
<term>Animal</term>
<term>Lapin</term>
<term>Oeil</term>
<term>Ophtalmologie</term>
<term>Implant</term>
<term>Hydrophilie</term>
<term>Lentille intraoculaire</term>
<term>Bord</term>
<term>Chirurgie</term>
<term>Traitement</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Lapin</term>
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<front><div type="abstract" xml:lang="en">Purpose: To evaluate the development of posterior capsule opacification (PCO) after implantation of single-piece hydrophilic acrylic intraocular lenses (lOLs) with an enhanced square edge. Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. Methods: The standard 570H Centerflex (Rayner Ltd.) design was compared to 2 new designs with enhanced square edges: the 570E and the 570C. Ten lOLs of each type were implanted in a randomized manner by the same surgeon in 15 pigmented rabbits. After a follow-up of 3 weeks, the rabbits were killed and the eyes were analyzed from the posterior view. The intensity of central PCO, peripheral PCO, and Soemmering's ring formation was graded from 0 to 4. The area of Soemmering's ring was graded from 0 to 4 based on the number of quadrants involved. Other parameters analyzed were capsulorhexis coverage of the IOL edge and IOL centration and fixation. Results from the posterior view were complemented by histopathological evaluation. Results: Posterior capsule opacification was lowest in the 570C group, highest in the 570H group, and intermediate in the 570E group. There was a statistically significant difference between the 3 groups in peripheral PCO (P = .039). No significant difference was found between the groups in the other parameters analyzed. When cell ingrowth occurred with the 570H, it started at the optic-haptic junctions, as observed during the clinical follow-up and confirmed by gross and histopathological analyses. Conclusions: The square optic edge is the most important IOL design feature for PCO prevention. However, it should be present for 360 degrees around the IOL optic to provide an effective barrier effect.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Utah</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Utah"><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
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<name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name>
<name sortKey="Davis, Brandon L" sort="Davis, Brandon L" uniqKey="Davis B" first="Brandon L." last="Davis">Brandon L. Davis</name>
<name sortKey="Izak, Andrea M" sort="Izak, Andrea M" uniqKey="Izak A" first="Andrea M." last="Izak">Andrea M. Izak</name>
<name sortKey="Mamalis, Nick" sort="Mamalis, Nick" uniqKey="Mamalis N" first="Nick" last="Mamalis">Nick Mamalis</name>
<name sortKey="Nilson, Christian D" sort="Nilson, Christian D" uniqKey="Nilson C" first="Christian D." last="Nilson">Christian D. Nilson</name>
<name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K." last="Pandey">Suresh K. Pandey</name>
<name sortKey="Weight, Christopher" sort="Weight, Christopher" uniqKey="Weight C" first="Christopher" last="Weight">Christopher Weight</name>
</country>
</tree>
</affiliations>
</record>

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   |area=    HapticV1
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   |clé=     Pascal:05-0001728
   |texte=   Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge
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Serveur d'exploration sur les dispositifs haptiques

Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge

Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge

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	Serveur d'exploration sur les dispositifs haptiques
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